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Kicker Joey Slye was among those pointing the finger at themselves afterward.
The Vikings rallied from an 11-point fourth-quarter deficit.
Carolina will play at Green Bay on Dec. 19 at 8:15 p.m. ET.
Carolina pitched its first shutout since 2015.
P.J. Walker will get his first NFL start.
But McCaffrey came out during Carolina's final drive with an apparent upper-body injury.
Joey Slye's 67-yard field goal attempt sailed wide right as time expired.
Carolina forced just one punt in the game.